Name | o-Amino Benzaldehyde |
Synonyms | ANTHRANILALDEHYDE O-AMINOBENZALDEHYDE 2-amino-benzaldehyd 2-Aminobenzaldeyhde 2-Aminobenzaldehyde o-Amino Benzaldehyde Benzaldehyde,2-amino- Benzaldehyde, 2-amino- ORTHO-AMINOBENZALDEHYDE o-Amino Benzaldehyde 2-Amino Benzaldehyde |
CAS | 529-23-7 |
EINECS | 208-454-3 |
InChI | InChI=1/C7H7NO/c8-7-4-2-1-3-6(7)5-9/h1-5H,8H2 |
Molecular Formula | C7H7NO |
Molar Mass | 121.14 |
Density | 1.1344 (rough estimate) |
Melting Point | 38°C |
Boling Point | 225.84°C (rough estimate) |
Flash Point | 113°C |
Vapor Presure | 0.0135mmHg at 25°C |
Appearance | Low Melting Solid |
Color | White to yellow |
pKa | -0.01±0.10(Predicted) |
Storage Condition | -20°C |
Stability | Unstable: reported to polymerize rapidly at room temperature. Incompatible with strong oxidizing agents, strong bases. Store at -20 C. |
Refractive Index | 1.5323 (estimate) |
MDL | MFCD00007709 |
Physical and Chemical Properties | O-aminobenzaldehyde is white crystal, melting point 39-42 ℃, boiling point 80-85 ℃(0.27kPa). Slightly soluble in cold water, soluble in ethanol, ether, chloroform and benzene. Can be volatilized with water vapor, easy to polymerization. |
Use | Determination of codeine. Biochemical research. Organic synthesis. Dye intermediates. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-10-23 |
HS Code | 29223990 |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
overview | o-aminobenzaldehyde is an important intermediate and is widely used in fine chemical and pharmaceutical fields. In medicine, it can further synthesize 2-amino -3,5 dibromobenzaldehyde, and it is a very important intermediate for the synthesis of ambroxol (ambroxol). |
use | o-aminobenzaldehyde is a commonly used organic synthesis intermediate, dye raw material and pharmaceutical raw material, and is an important raw material for the synthesis of quinoline anti-inflammatory and antiviral drugs. o-aminobenzaldehyde is also an important pharmaceutical intermediate and fine chemical material for the synthesis of ambroxol. Determination of codeine. Biochemical research. Organic synthesis. Dye intermediates. |
production method | o-nitrobenzaldehyde is obtained by reducing ferrous sulfate and ammonia; ferrous sulfate heptahydrate, concentrated hydrochloric acid, water and o-nitrobenzaldehyde are added to the reactor, stirred and heated, when the temperature of the mixture reaches 90 ℃, concentrated ammonia water is added at one time, and ammonia water is added in three batches. After the feeding is completed, the water vapor mixture is distilled, and the distillate is saturated with sodium chloride and cooled, filtered finished product. |